An aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone, a major mammalian estrogen. It is converted from ANDROSTENEDIONE directly, or from TESTOSTERONE via ESTRADIOL. In humans, it is produced primarily by the cyclic ovaries, PLACENTA, and the ADIPOSE TISSUE of men and postmenopausal women.
Estrone has been studied across 19 research domains including 🧬 Hormones, 🔬 Oncology, 🫁 Liver & Detox, 🔥 Metabolic, ♀♂ Sexual Health. The primary research focus is 🧬 Hormones with 54% of studies addressing this area.
The following compounds share molecular targets with Estrone, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.
This evidence profile for Estrone is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.
Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.