BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
BiohacksAI is an evolving scientific literature platform. New compounds and evidence are indexed continuously.
B

Estrone

An aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone, a major mammalian estrogen. It is converted from ANDROSTENEDIONE directly, or from TESTOSTERONE via ESTRADIOL. In humans, it is produced primarily by the cyclic ovaries, PLACENTA, and the ADIPOSE TISSUE of men and postmenopausal women.

300+ PubMed studies analyzed · 4 RCTs · Evidence Score: 44.7

Research Domains

Estrone has been studied across 19 research domains including 🧬 Hormones, 🔬 Oncology, 🫁 Liver & Detox, 🔥 Metabolic, ♀♂ Sexual Health. The primary research focus is 🧬 Hormones with 54% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Estrone, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

Norethindrone
16 shared targets
Estriol
12 shared targets
Dehydroepiandrosterone
14 shared targets
Dehydroepiandrosterone
14 shared targets
Zearalenone
19 shared targets
Nandrolone
12 shared targets
Levonorgestrel
16 shared targets
Norgestrel
16 shared targets
17-alpha-Hydroxyprogesterone
12 shared targets
Methyltestosterone
14 shared targets
Loading evidence profile...

This evidence profile for Estrone is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.