Question 1

What compounds target PHOSPHOLIPID?

Accepted Answer

BiohacksAI has identified 24 compounds that interact with PHOSPHOLIPID (Phospholipid hydroperoxide glutathione peroxidase GPX4 (human)). Top compounds include: amlexanox, obeticholic acid [Supplementary Concept], Mepentol [Supplementary Concept], Tannins Polyphenolic compounds with molecular weights of around 500-3000 daltons and containing enough hydroxyl groups (1-2 per 100 MW) for effective cross linking of other compounds (ASTRINGENTS)., Vitamin. Each compound is ranked by evidence score derived from PubMed bioassay confidence and assay count.

Question 2

What is PHOSPHOLIPID (Phospholipid hydroperoxide glutathione)?

Accepted Answer

PHOSPHOLIPID is Phospholipid hydroperoxide glutathione peroxidase GPX4 (human). It is a molecular target for 24 compounds documented in PubMed bioassay data. UniProt ID: P36969.

#	Compound	Confidence	Active Assays
1	amlexanox	1.10	2
2	obeticholic acid [Supplementary Concept]	0.69	1
3	Mepentol [Supplementary Concept]	0.69	1
4	Tannins Polyphenolic compounds with molecular weights of around 500-3000 daltons and containing enough hydroxyl groups (1-2 per 100 MW) for effective cross linking of other compounds (ASTRINGENTS).	0.69	1
5	Vitamin	0.69	1
6	Camptothecin	0.69	1
7	candesartan cilexetil [Supplementary Concept]	0.69	1
8	cannabidiol	0.69	1
9	Cefotetan	0.69	1
10	Cephaloglycin	0.69	1
11	Cisplatin	0.69	1
12	Dipyrone	0.69	1
13	Dithiazanine 3-Ethyl-2-(5-(3-ethyl-2-benzothiazolinylidene)-1,3- pentadienyl)benzothiazolium.	0.69	1
14	Ethoxyquin Antioxidant; also	0.69	1
15	gamma-Linolenic Acid	0.69	1
16	Gestrinone	0.69	1
17	Hexachlorophene	0.69	1
18	Lypressin	0.69	1
19	Methyldopa	0.69	1
20	Masoprocol	0.69	1
21	Ornipressin	0.69	1
22	stx64	0.69	1
23	Trenbolone Acetate	0.69	1
24	Triiodothyronine	0.69	1

BiohacksAI

PHOSPHOLIPID

Compounds Targeting PHOSPHOLIPID

About PHOSPHOLIPID as a Drug Target