What compounds target PRKCD?

BiohacksAI has identified 40 compounds that interact with PRKCD (protein kinase C, delta). Top compounds include: tofacitinib, alvocidib, bosutinib, doramapimod, midostaurin. Each compound is ranked by evidence score derived from PubMed bioassay confidence and assay count.

What is PRKCD (protein kinase C,)?

PRKCD is protein kinase C, delta. It is a molecular target for 40 compounds documented in PubMed bioassay data. UniProt ID: P09215. NCBI Gene ID: 170538.

PRKCD

MOLECULAR TARGET

protein kinase C, delta

UniProt: P09215 NCBI Gene: 17053840 compounds

PRKCD (protein kinase C, delta) is targeted by 40 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).

Compounds Targeting PRKCD

Ranked by bioassay confidence score (PubChem active assay count × evidence quality).

#	Compound	Confidence	Active Assays
1	tofacitinib	4.65	104
2	alvocidib	4.52	91
3	bosutinib	4.08	58
4	doramapimod	4.06	57
5	midostaurin	3.85	46
6	abemaciclib	3.66	38
7	fasudil	3.66	38
8	baricitinib	3.56	34
9	pelitinib	3.50	32
10	tae 684	3.43	30
11	gf 109203	3.40	29
12	rottlerin	3.26	25
13	jnj 7706621	3.09	21
14	lestaurtinib	3.04	20
15	pf 03758309	3.00	19
16	ruboxistaurin	2.94	18
17	go 6976	2.89	17
18	r 406	2.83	16
19	pf 00562271	2.77	15
20	sotrastaurin	2.77	15
21	capivasertib	2.77	15
22	curcumin pyrazole	2.77	15
23	crenolanib	2.71	14
24	gsk 690693	2.64	13
25	zotiraciclib	2.56	12
26	gsk 461364	2.40	10
27	ripasudil	2.40	10
28	azd 7762	2.30	9
29	bms 754807	2.30	9
30	balanol	2.30	9
31	decernotinib	2.20	8
32	y 39983	2.20	8
33	enzastaurin	2.08	7
34	amg 900	2.08	7
35	ucn 01	1.79	5
36	sar 407899 free base	1.79	5
37	hydroxyfasudil [Supplementary Concept]	1.39	3
38	myricetin-3-O-galactopyranoside [Supplementary Concept]	0.69	1
39	alsterpaullone	0.69	1
40	Sphingosine	0.69	1

About PRKCD as a Drug Target

PRKCD (protein kinase C, delta) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 40 compounds with documented PRKCD interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.

PRKCD inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.