What compounds target PTGER2?

BiohacksAI has identified 28 compounds that interact with PTGER2 (prostaglandin E receptor 2). Top compounds include: Dinoprostone, Alprostadil, Celecoxib, Dinoprost, Calcimycin. Each compound is ranked by evidence score derived from PubMed bioassay confidence and assay count.

What is PTGER2 (prostaglandin E receptor)?

PTGER2 is prostaglandin E receptor 2. It is a molecular target for 28 compounds documented in PubMed bioassay data. UniProt ID: P43116. NCBI Gene ID: 5732.

PTGER2

MOLECULAR TARGET

prostaglandin E receptor 2

UniProt: P43116 NCBI Gene: 573228 compounds

PTGER2 (prostaglandin E receptor 2) is targeted by 28 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).

Compounds Targeting PTGER2

Ranked by bioassay confidence score (PubChem active assay count × evidence quality).

#	Compound	Confidence	Active Assays
1	Dinoprostone	3.58	35
2	Alprostadil	2.20	8
3	Celecoxib	1.39	3
4	Dinoprost	1.39	3
5	Calcimycin	1.10	2
6	Disulfiram	1.10	2
7	Vitamin K 3	1.10	2
8	Misoprostol	1.10	2
9	Nitroarginine	1.10	2
10	Prostaglandin D2	1.10	2
11	Methylene Blue	0.69	1
12	plumbagin [Supplementary Concept]	0.69	1
13	Levalbuterol	0.69	1
14	Levalbuterol	0.69	1
15	Carvedilol	0.69	1
16	celastrol	0.69	1
17	Cetylpyridinium Cationic bactericidal surfactant used as	0.69	1
18	Cyclic AMP	0.69	1
19	Cyclic AMP	0.69	1
20	Hexachlorophene	0.69	1
21	Iloprost	0.69	1
22	Metaproterenol	0.69	1
23	Norepinephrine Precursor of epinephrine that is secreted by	0.69	1
24	Noscapine	0.69	1
25	p-Azobenzenearsonate	0.69	1
26	Salmeterol Xinafoate	0.69	1
27	Silymarin	0.69	1
28	trequinsin hydrochloride	0.69	1

About PTGER2 as a Drug Target

PTGER2 (prostaglandin E receptor 2) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 28 compounds with documented PTGER2 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.

PTGER2 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.