What compounds target RARB?

BiohacksAI has identified 18 compounds that interact with RARB (retinoic acid receptor beta). Top compounds include: tretinoin, alitretinoin, bexarotene, o demethylated adapalene, tazarotene. Each compound is ranked by evidence score derived from PubMed bioassay confidence and assay count.

What is RARB (retinoic acid receptor)?

RARB is retinoic acid receptor beta. It is a molecular target for 18 compounds documented in PubMed bioassay data. UniProt ID: P10826. NCBI Gene ID: 5915.

RARB

MOLECULAR TARGET

retinoic acid receptor beta

UniProt: P10826 NCBI Gene: 591518 compounds

RARB (retinoic acid receptor beta) is targeted by 18 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).

Compounds Targeting RARB

Ranked by bioassay confidence score (PubChem active assay count × evidence quality).

#	Compound	Confidence	Active Assays
1	tretinoin	5.16	174
2	alitretinoin	4.03	55
3	bexarotene	4.03	55
4	o demethylated adapalene	2.77	15
5	tazarotene	1.79	5
6	Adapalene	1.61	4
7	Triiodothyronine	1.10	2
8	Progesterone	0.69	1
9	Calcitriol	0.69	1
10	Gemfibrozil	0.69	1
11	bdb 4 e 2 3 adamantan 1 yl 4 hydroxy phenyl propenyl benzoic acid chembl421773	0.69	1
12	bdb 4 e 2 3 adamantan 1 yl 4 hydroxy phenyl vinyl benzoic acid chembl146646	0.69	1
13	bdb 4 e 2 3 adamantan 1 yl 4 methoxy phenyl propenyl benzoic acid chembl146449	0.69	1
14	bdb 6 3 adamantan 1 yl 4 1 2 dihydroxy ethyl phenyl naphthalene 2 carboxylic acid ch	0.69	1
15	bdb 6 3 adamantan 1 yl 4 2 3 dihydroxy propoxy phenyl naphthalene 2 carboxylic acid	0.69	1
16	bdb 6 3 adamantan 1 yl 4 2 3 dihydroxy propyl phenyl naphthalene 2 carboxylic acid c	0.69	1
17	bdb 6 3 adamantan 1 yl 4 3 hydroxy propyl phenyl naphthalene 2 carboxylic acid chemb	0.69	1
18	bdb 6 3 adamantan 1 yl 4 hydroxymethyl phenyl naphthalene 2 carboxylic acid chembl42	0.69	1

About RARB as a Drug Target

RARB (retinoic acid receptor beta) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 18 compounds with documented RARB interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.

RARB inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.