SLCO1B1
MOLECULAR TARGETsolute carrier organic anion transporter family member 1B1
SLCO1B1 (solute carrier organic anion transporter family member 1B1) is targeted by 25 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting SLCO1B1
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | Ritonavir | 1.79 | 5 |
| 2 | Atorvastatin | 1.61 | 4 |
| 3 | Simvastatin | 1.39 | 3 |
| 4 | Bilirubin | 1.39 | 3 |
| 5 | Pravastatin | 1.39 | 3 |
| 6 | Rifamycins | 1.39 | 3 |
| 7 | Rifamycins | 1.39 | 3 |
| 8 | Arachidonic Acid | 1.10 | 2 |
| 9 | Genistein | 1.10 | 2 |
| 10 | Losartan | 1.10 | 2 |
| 11 | Tannins Polyphenolic compounds with molecular weights of around 500-3000 daltons and containing enough hydroxyl groups (1-2 per 100 MW) for effective cross linking of other compounds (ASTRINGENTS). | 1.10 | 2 |
| 12 | beta Carotene | 1.10 | 2 |
| 13 | candesartan cilexetil [Supplementary Concept] | 1.10 | 2 |
| 14 | Gemfibrozil | 1.10 | 2 |
| 15 | Glyburide | 1.10 | 2 |
| 16 | Mometasone Furoate | 1.10 | 2 |
| 17 | Olmesartan Medoxomil | 1.10 | 2 |
| 18 | Thyroxine | 0.69 | 1 |
| 19 | Sirolimus | 0.69 | 1 |
| 20 | Antimycin | 0.69 | 1 |
| 21 | Digoxin | 0.69 | 1 |
| 22 | Silymarin | 0.69 | 1 |
| 23 | Taurocholic Acid | 0.69 | 1 |
| 24 | Thyroxine | 0.69 | 1 |
| 25 | Triiodothyronine | 0.69 | 1 |
About SLCO1B1 as a Drug Target
SLCO1B1 (solute carrier organic anion transporter family member 1B1) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 25 compounds with documented SLCO1B1 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
SLCO1B1 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.