TTR
MOLECULAR TARGETtransthyretin
TTR (transthyretin) is targeted by 17 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting TTR
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | Niflumic Acid | 1.79 | 5 |
| 2 | Apigenin 5,7,4'-trihydroxy-flavone, | 1.61 | 4 |
| 3 | Thyroxine | 1.61 | 4 |
| 4 | Luteolin 5,7,3',4'-tetrahydroxy-flavone, | 1.61 | 4 |
| 5 | pterostilbene | 1.61 | 4 |
| 6 | piceatannol | 1.61 | 4 |
| 7 | Thyroxine | 1.61 | 4 |
| 8 | egcg | 1.39 | 3 |
| 9 | Masoprocol | 1.39 | 3 |
| 10 | Genistein | 0.69 | 1 |
| 11 | Kaempferols | 0.69 | 1 |
| 12 | Resveratrol | 0.69 | 1 |
| 13 | Rosmarinic Acid | 0.69 | 1 |
| 14 | Vitamin | 0.69 | 1 |
| 15 | Dextrothyroxine | 0.69 | 1 |
| 16 | Gemfibrozil | 0.69 | 1 |
| 17 | Triiodothyronine | 0.69 | 1 |
About TTR as a Drug Target
TTR (transthyretin) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 17 compounds with documented TTR interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
TTR inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.