TXNRD1
MOLECULAR TARGETthioredoxin reductase 1
TXNRD1 (thioredoxin reductase 1) is targeted by 21 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting TXNRD1
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | Azathioprine | 1.39 | 3 |
| 2 | Cisplatin | 1.10 | 2 |
| 3 | Dinitrochlorobenzene | 1.10 | 2 |
| 4 | Pueraria | 0.69 | 1 |
| 5 | myricetin-3-O-galactopyranoside [Supplementary Concept] | 0.69 | 1 |
| 6 | Vitamin | 0.69 | 1 |
| 7 | Anisomycin | 0.69 | 1 |
| 8 | Diiodotyrosine | 0.69 | 1 |
| 9 | Ethylmaleimide | 0.69 | 1 |
| 10 | Chlorophyll Binding Proteins | 0.69 | 1 |
| 11 | hydroxyindoleacetic acid | 0.69 | 1 |
| 12 | Idazoxan | 0.69 | 1 |
| 13 | Isoproterenol Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on | 0.69 | 1 |
| 14 | Levodopa | 0.69 | 1 |
| 15 | Methyldopa | 0.69 | 1 |
| 16 | Methysergide | 0.69 | 1 |
| 17 | Nitrofurazone | 0.69 | 1 |
| 18 | Oxyphenbutazone | 0.69 | 1 |
| 19 | Oxytetracycline | 0.69 | 1 |
| 20 | Promethazine | 0.69 | 1 |
| 21 | tyrphostin 9 | 0.69 | 1 |
About TXNRD1 as a Drug Target
TXNRD1 (thioredoxin reductase 1) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 21 compounds with documented TXNRD1 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
TXNRD1 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.