Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells
REACTOME PATHWAYThe Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells pathway (Reactome ID: R-HSA-210744) involves 4 genes and is affected by 28 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | plumbagin [Supplementary Concept] | — | 300 |
| 2 | egcg | — | 300 |
| 3 | Aurintricarboxylic Acid | — | 184 |
| 4 | juglone hydroxylase [Supplementary Concept] catalyzes | — | 279 |
| 5 | DEAD-box RNA Helicases | — | 169 |
| 6 | Thioctic Acid | — | 298 |
| 7 | Arachidonic Acid | — | 245 |
| 8 | Oleic Acid | — | 112 |
| 9 | alpha-Linolenic Acid | — | 300 |
| 10 | candesartan cilexetil [Supplementary Concept] | — | 300 |
| 11 | Cisplatin | — | 300 |
| 12 | diallyl trisulfide | — | 246 |
| 13 | Estramustine | — | 300 |
| 14 | gamma-Linolenic Acid | — | 300 |
| 15 | Hexachlorophene | — | 300 |
| 16 | Iodoacetamide | — | 300 |
| 17 | Lithocholic Acid | — | 300 |
| 18 | Oxytetracycline | — | 300 |
| 19 | rafoxanide | — | 172 |
| 20 | Ritonavir | — | 298 |
| 21 | Thioctic Acid | — | 300 |
| 22 | Trazodone | — | 297 |
| 23 | Papaverine | — | 299 |
| 24 | Colchicine | — | 300 |
| 25 | Etazolate | — | 66 |
| 26 | Nocodazole Nocodazole is | — | 215 |
| 27 | 11-hydroxypalmatine [Supplementary Concept] | — | 238 |
| 28 | np1 | — | 81 |
About the Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells Pathway
The Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells pathway is catalogued in Reactome (ID: R-HSA-210744) and involves 4 genes. In the BiohacksAI corpus, 28 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include CREBBP, EP300, KAT2A, KAT2B.