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BiohacksAI

Evidence-Based Biohacking

Patent Pending

Synthesis of Hepoxilins (HX) and Trioxilins (TrX)

REACTOME PATHWAY
Reactome: R-HSA-21426961 genes28 compounds

The Synthesis of Hepoxilins (HX) and Trioxilins (TrX) pathway (Reactome ID: R-HSA-2142696) involves 1 genes and is affected by 28 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.

Genes in this Pathway

ALOX12

Compounds Affecting Synthesis of Hepoxilins (HX) and Trioxilins (TrX)

#CompoundTargets HitStudies
1Quercetin300
2Masoprocol300
3fisetin78
4Tyrosine43
5Luteolin 5,7,3',4'-tetrahydroxy-flavone,150
6Tyrosine300
7butein158
8celastrol300
9Chlorhexidine299
10Ciclopirox88
11Diiodotyrosine300
12Disulfiram297
13Epinephrine299
14Flecainide297
15Fomepizole298
16Gliclazide300
17Hexachlorophene300
18isoetharine112
19Kynurenic Acid300
20mg6243
21Phenelzine297
22piceatannol300
23Piribedil300
24Procarbazine299
25Rimonabant300
26scriptaid53
27Dipyrone298
28ethopropazine hydrochloride2

About the Synthesis of Hepoxilins (HX) and Trioxilins (TrX) Pathway

The Synthesis of Hepoxilins (HX) and Trioxilins (TrX) pathway is catalogued in Reactome (ID: R-HSA-2142696) and involves 1 genes. In the BiohacksAI corpus, 28 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include ALOX12.