Retinoid cycle disease events
REACTOME PATHWAYThe Retinoid cycle disease events pathway (Reactome ID: R-HSA-2453864) involves 4 genes and is affected by 19 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Retinoid cycle disease events
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Vitamin | — | 295 |
| 2 | Niflumic Acid | — | 300 |
| 3 | Apigenin 5,7,4'-trihydroxy-flavone, | — | 300 |
| 4 | Thyroxine | — | 994 |
| 5 | Luteolin 5,7,3',4'-tetrahydroxy-flavone, | — | 150 |
| 6 | pterostilbene | — | 299 |
| 7 | piceatannol | — | 300 |
| 8 | Thyroxine | — | 300 |
| 9 | egcg | — | 300 |
| 10 | Masoprocol | — | 300 |
| 11 | Genistein | — | 300 |
| 12 | Kaempferols | — | 300 |
| 13 | Resveratrol | — | 298 |
| 14 | Rosmarinic Acid | — | 300 |
| 15 | Dextrothyroxine | — | 134 |
| 16 | Gemfibrozil | — | 297 |
| 17 | Triiodothyronine | — | 300 |
| 18 | Hexachlorophene | — | 300 |
| 19 | Retinaldehyde | — | 300 |
About the Retinoid cycle disease events Pathway
The Retinoid cycle disease events pathway is catalogued in Reactome (ID: R-HSA-2453864) and involves 4 genes. In the BiohacksAI corpus, 19 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include NAPEPLD, OPN1LW, RBP4, TTR.