Platelet sensitization by LDL
REACTOME PATHWAYThe Platelet sensitization by LDL pathway (Reactome ID: R-HSA-432142) involves 5 genes and is affected by 16 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Platelet sensitization by LDL
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Sorafenib | — | 300 |
| 2 | Dasatinib | — | 299 |
| 3 | tyrphostin ag 1478 | — | 4 |
| 4 | Okadaic Acid | — | 300 |
| 5 | Afatinib | — | 297 |
| 6 | egcg | — | 300 |
| 7 | fisetin | — | 78 |
| 8 | myricetin-3-O-galactopyranoside [Supplementary Concept] | — | 300 |
| 9 | Quercetin | — | 300 |
| 10 | Anisomycin | — | 247 |
| 11 | Celecoxib | — | 295 |
| 12 | isorhamnetin-3-O-beta-D-glucopyranosyl-(1-3)-alpha-L-rhamnopyranosyl-(1-6)-beta-D-galactopyranoside [Supplementary Concept] from | — | 300 |
| 13 | withaferin | — | 300 |
| 14 | Axitinib | — | 298 |
| 15 | Crizotinib | — | 298 |
| 16 | celastrol | — | 300 |
About the Platelet sensitization by LDL Pathway
The Platelet sensitization by LDL pathway is catalogued in Reactome (ID: R-HSA-432142) and involves 5 genes. In the BiohacksAI corpus, 16 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include FGR, MAPK14, PPP2CA, PPP2R5A, PTPN6.