RHOJ GTPase cycle
REACTOME PATHWAYThe RHOJ GTPase cycle pathway (Reactome ID: R-HSA-9013409) involves 8 genes and is affected by 16 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting RHOJ GTPase cycle
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | pictilisib | — | 25 |
| 2 | ly294002 | — | 11 |
| 3 | Sirolimus | — | 300 |
| 4 | torin 1 | — | 10 |
| 5 | Dasatinib | — | 299 |
| 6 | alsterpaullone | — | 12 |
| 7 | kenpaullone | — | 8 |
| 8 | Axitinib | — | 298 |
| 9 | Wortmannin | — | 300 |
| 10 | alpelisib | — | 227 |
| 11 | Quercetin | — | 300 |
| 12 | Hydrocortisone | — | 299 |
| 13 | Hydrocortisone | — | 298 |
| 14 | Guanosine Diphosphate | — | 300 |
| 15 | Guanosine Triphosphate Guanosine 5'-(tetrahydrogen triphosphate). | — | 300 |
| 16 | casin | — | 10 |
About the RHOJ GTPase cycle Pathway
The RHOJ GTPase cycle pathway is catalogued in Reactome (ID: R-HSA-9013409) and involves 8 genes. In the BiohacksAI corpus, 16 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include ARHGAP35, CDC42, CDC42BPA, CDC42BPB, PAK4.