BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
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Cortisol

The main glucocorticoid secreted by the ADRENAL CORTEX. Its synthetic counterpart is used, either as an injection or topically, in the treatment of inflammation, allergy, collagen diseases, asthma, adrenocortical deficiency, shock, and some neoplastic conditions.

299+ PubMed studies analyzed · 17 RCTs · Evidence Score: 51.3

Research Domains

Cortisol has been studied across 23 research domains including 🧘 Stress & Anxiety, 🧬 Hormones, 😴 Sleep, 🫘 Kidney, 🌤️ Mood & Depression. The primary research focus is 🧘 Stress & Anxiety with 100% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Cortisol, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

Hydrocortisone
16 shared targets
stanolone
6 shared targets
Pregnenolone
8 shared targets
Fludrocortisone
6 shared targets
Melengestrol
9 shared targets
Methandrostenolone
7 shared targets
Flumethasone
7 shared targets
Fluorometholone
8 shared targets
Androstenedione
8 shared targets
17-alpha-Hydroxyprogesterone
8 shared targets
Loading evidence profile...

This evidence profile for Cortisol is generated deterministically from 299 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.