Dengue Virus Attachment and Entry
REACTOME PATHWAYThe Dengue Virus Attachment and Entry pathway (Reactome ID: R-HSA-9918485) involves 8 genes and is affected by 20 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Dengue Virus Attachment and Entry
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Crizotinib | — | 298 |
| 2 | Quercetin | — | 300 |
| 3 | Sorafenib | — | 300 |
| 4 | Axitinib | — | 298 |
| 5 | pictilisib | — | 25 |
| 6 | Wortmannin | — | 300 |
| 7 | ly294002 | — | 11 |
| 8 | alpelisib | — | 227 |
| 9 | Sirolimus | — | 300 |
| 10 | torin 1 | — | 10 |
| 11 | Afatinib | — | 297 |
| 12 | Dasatinib | — | 299 |
| 13 | Hexachlorophene | — | 300 |
| 14 | Adenosine Diphosphate Adenosine 5'-(trihydrogen diphosphate). | — | 300 |
| 15 | Ergosterol | — | 300 |
| 16 | sp600125 | — | 117 |
| 17 | Diminazene | — | 300 |
| 18 | silver sulfadiazine | — | 299 |
| 19 | egcg | — | 300 |
| 20 | Podophyllotoxin | — | 14 |
About the Dengue Virus Attachment and Entry Pathway
The Dengue Virus Attachment and Entry pathway is catalogued in Reactome (ID: R-HSA-9918485) and involves 8 genes. In the BiohacksAI corpus, 20 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include AXL, FURIN, HSPA5, MERTK, PIK3R1.