ABCG2
MOLECULAR TARGETATP binding cassette subfamily G member 2 (JR blood group)
ABCG2 (ATP binding cassette subfamily G member 2 (JR blood group)) is targeted by 22 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting ABCG2
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | licochalcone | 3.30 | 26 |
| 2 | Quercetin | 1.95 | 6 |
| 3 | Harmine Alkaloid isolated from seeds of PEGANUM HARMALA; ZYGOPHYLLACEAE. It is identical to banisterine, or telepathine, from Banisteria caapi and is | 1.61 | 4 |
| 4 | Apigenin 5,7,4'-trihydroxy-flavone, | 1.10 | 2 |
| 5 | chrysin | 1.10 | 2 |
| 6 | Genistein | 1.10 | 2 |
| 7 | Kaempferols | 1.10 | 2 |
| 8 | 3',4'-didemethylnobiletin [Supplementary Concept] | 1.10 | 2 |
| 9 | Atorvastatin | 0.69 | 1 |
| 10 | Luteolin 5,7,3',4'-tetrahydroxy-flavone, | 0.69 | 1 |
| 11 | Sirolimus | 0.69 | 1 |
| 12 | Avapritinib | 0.69 | 1 |
| 13 | candesartan cilexetil [Supplementary Concept] | 0.69 | 1 |
| 14 | Caspofungin | 0.69 | 1 |
| 15 | Daunorubicin | 0.69 | 1 |
| 16 | Delavirdine | 0.69 | 1 |
| 17 | Estrone | 0.69 | 1 |
| 18 | Febuxostat | 0.69 | 1 |
| 19 | Fenofibrate | 0.69 | 1 |
| 20 | Furosemide | 0.69 | 1 |
| 21 | Sorafenib | 0.69 | 1 |
| 22 | Topotecan | 0.69 | 1 |
About ABCG2 as a Drug Target
ABCG2 (ATP binding cassette subfamily G member 2 (JR blood group)) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 22 compounds with documented ABCG2 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
ABCG2 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.