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Topotecan

An antineoplastic agent used to treat ovarian cancer. It works by inhibiting DNA TOPOISOMERASES, TYPE I.

300+ PubMed studies analyzed · 25 RCTs · Evidence Score: 51.6

Research Domains

Topotecan has been studied across 13 research domains including 🔬 Oncology, 🧬 Hormones, 🫁 Liver & Detox, 👁️ Vision & Eye, ⏳ Longevity & Aging. The primary research focus is 🔬 Oncology with 74% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Topotecan, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

darapladib
9 shared targets
Irinotecan
10 shared targets
Puromycin
7 shared targets
celastrol
14 shared targets
Epirubicin
7 shared targets
monorden
7 shared targets
Deslanoside
7 shared targets
Teniposide
6 shared targets
Camptothecin
14 shared targets
withaferin
7 shared targets
Loading evidence profile...

This evidence profile for Topotecan is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.