What compounds target CA9?

BiohacksAI has identified 34 compounds that interact with CA9 (carbonic anhydrase 9). Top compounds include: Sulfanilamide, Celecoxib, Zonisamide, Mafenide, Phenol. Each compound is ranked by evidence score derived from PubMed bioassay confidence and assay count.

What is CA9 (carbonic anhydrase 9)?

CA9 is carbonic anhydrase 9. It is a molecular target for 34 compounds documented in PubMed bioassay data. UniProt ID: Q16790. NCBI Gene ID: 768.

CA9

MOLECULAR TARGET

carbonic anhydrase 9

UniProt: Q16790 NCBI Gene: 76834 compounds

CA9 (carbonic anhydrase 9) is targeted by 34 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).

Compounds Targeting CA9

Ranked by bioassay confidence score (PubChem active assay count × evidence quality).

#	Compound	Confidence	Active Assays
1	Sulfanilamide	3.22	24
2	Celecoxib	2.83	16
3	Zonisamide	2.77	15
4	Mafenide	2.40	10
5	Phenol	2.30	9
6	Sulpiride	2.08	7
7	benzolamide	1.95	6
8	Indapamide	1.95	6
9	Chlorthalidone	1.61	4
10	Histidine	1.39	3
11	Furosemide	1.39	3
12	Probenecid	1.39	3
13	chrysin	1.10	2
14	Bumetanide	1.10	2
15	Vanillic Acid	1.10	2
16	Metolazone	1.10	2
17	stx64	1.10	2
18	caffeic acid	0.69	1
19	Catechin	0.69	1
20	Quercetin	0.69	1
21	Resveratrol	0.69	1
22	Spermidine	0.69	1
23	Bortezomib	0.69	1
24	Carbonic Acid Carbonic acid (H2C03).	0.69	1
25	d609	0.69	1
26	Famotidine	0.69	1
27	Hydrogen Cyanide Hydrogen cyanide (HCN);	0.69	1
28	Hydrogen Sulfide	0.69	1
29	Hydrogen Sulfide	0.69	1
30	Lacosamide	0.69	1
31	ninhydrin	0.69	1
32	4-Hydroxybenzoate-3-Monooxygenase	0.69	1
33	Sodium Azide	0.69	1
34	Sulfides Chemical groups containing	0.69	1

About CA9 as a Drug Target

CA9 (carbonic anhydrase 9) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 34 compounds with documented CA9 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.

CA9 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.