A benzisoxazole and sulfonamide derivative that acts as a CALCIUM CHANNEL blocker. It is used primarily as an adjunctive antiepileptic agent for the treatment of PARTIAL SEIZURES, with or without secondary generalization.
Zonisamide has been studied across 20 research domains including 🧠 Neuroprotection, 💊 Pain, 😴 Sleep, 🌤️ Mood & Depression, 🔬 Inflammation. The primary research focus is 🧠 Neuroprotection with 15% of studies addressing this area.
The following compounds share molecular targets with Zonisamide, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.
This evidence profile for Zonisamide is generated deterministically from 297 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.
Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.