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Chlorthalidone

A benzenesulfonamide-phthalimidine that tautomerizes to a BENZOPHENONES form. It is considered a thiazide-like diuretic.

299+ PubMed studies analyzed · 59 RCTs · Evidence Score: 51.2

Research Domains

Chlorthalidone has been studied across 13 research domains including ❤️ Cardiovascular, 🫘 Kidney, 🔥 Metabolic, 🦴 Bone & Joint, 😴 Sleep. The primary research focus is ❤️ Cardiovascular with 69% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Chlorthalidone, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

24
10 shared targets
trichlormethiazide
10 shared targets
trientine
10 shared targets
topiramate
10 shared targets
brinzolamide
10 shared targets
ethoxycoumarin
9 shared targets
Zonisamide
12 shared targets
benzolamide
11 shared targets
paraben
10 shared targets
syringic
10 shared targets
Loading evidence profile...

This evidence profile for Chlorthalidone is generated deterministically from 299 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.