What compounds target CBX1?

BiohacksAI has identified 29 compounds that interact with CBX1 (chromobox 1). Top compounds include: Disulfiram, Levodopa, piceatannol, myricetin-3-O-galactopyranoside [Supplementary Concept], ag490. Each compound is ranked by evidence score derived from PubMed bioassay confidence and assay count.

What is CBX1 (chromobox 1)?

CBX1 is chromobox 1. It is a molecular target for 29 compounds documented in PubMed bioassay data. UniProt ID: P83916. NCBI Gene ID: 10951.

CBX1

MOLECULAR TARGET

chromobox 1

UniProt: P83916 NCBI Gene: 1095129 compounds

CBX1 (chromobox 1) is targeted by 29 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).

Compounds Targeting CBX1

Ranked by bioassay confidence score (PubChem active assay count × evidence quality).

#	Compound	Confidence	Active Assays
1	Disulfiram	1.10	2
2	Levodopa	1.10	2
3	piceatannol	1.10	2
4	myricetin-3-O-galactopyranoside [Supplementary Concept]	0.69	1
5	ag490	0.69	1
6	Aurintricarboxylic Acid	0.69	1
7	Calcimycin	0.69	1
8	Cisplatin	0.69	1
9	Clotrimazole	0.69	1
10	Diamide	0.69	1
11	Emodin Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as	0.69	1
12	ethopropazine	0.69	1
13	Fluspirilene	0.69	1
14	Idarubicin	0.69	1
15	Isoproterenol Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on	0.69	1
16	Kynurenic Acid	0.69	1
17	ly294002	0.69	1
18	Metergoline	0.69	1
19	methionine sulfoximine	0.69	1
20	Methyldopa	0.69	1
21	Nisoldipine	0.69	1
22	Oxytetracycline	0.69	1
23	Papaverine	0.69	1
24	Perphenazine	0.69	1
25	Promethazine	0.69	1
26	Reserpine	0.69	1
27	Rotenone	0.69	1
28	Nitroprusside	0.69	1
29	tyrphostin 9	0.69	1

About CBX1 as a Drug Target

CBX1 (chromobox 1) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 29 compounds with documented CBX1 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.

CBX1 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.