KLF5
MOLECULAR TARGETKLF transcription factor 5
KLF5 (KLF transcription factor 5) is targeted by 9 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting KLF5
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | Ouabain | 1.79 | 5 |
| 2 | Digoxin | 1.61 | 4 |
| 3 | Camptothecin | 1.10 | 2 |
| 4 | Colchicine | 1.10 | 2 |
| 5 | colchine | 1.10 | 2 |
| 6 | Hexachlorophene | 1.10 | 2 |
| 7 | Podophyllotoxin | 1.10 | 2 |
| 8 | Digitoxin | 0.69 | 1 |
| 9 | Tripterygium | 0.69 | 1 |
About KLF5 as a Drug Target
KLF5 (KLF transcription factor 5) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 9 compounds with documented KLF5 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
KLF5 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.