TRHR
MOLECULAR TARGETthyrotropin releasing hormone receptor
TRHR (thyrotropin releasing hormone receptor) is targeted by 19 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting TRHR
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | Hexachlorophene | 2.30 | 9 |
| 2 | Riboflavin Nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables. | 1.79 | 5 |
| 3 | Lithocholic Acid | 1.61 | 4 |
| 4 | Cetylpyridinium Cationic bactericidal surfactant used as | 1.39 | 3 |
| 5 | Arecoline | 1.10 | 2 |
| 6 | Lovastatin | 1.10 | 2 |
| 7 | Thioridazine | 1.10 | 2 |
| 8 | Budesonide | 0.69 | 1 |
| 9 | 20-alpha-Dihydroprogesterone | 0.69 | 1 |
| 10 | Acetaldehyde | 0.69 | 1 |
| 11 | Calcimycin | 0.69 | 1 |
| 12 | candesartan cilexetil [Supplementary Concept] | 0.69 | 1 |
| 13 | Clotrimazole | 0.69 | 1 |
| 14 | Dihydrotestosterone | 0.69 | 1 |
| 15 | Monocrotaline | 0.69 | 1 |
| 16 | Niacin | 0.69 | 1 |
| 17 | Promethazine | 0.69 | 1 |
| 18 | Tinidazole | 0.69 | 1 |
| 19 | triflupromazine hydrochloride | 0.69 | 1 |
About TRHR as a Drug Target
TRHR (thyrotropin releasing hormone receptor) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 19 compounds with documented TRHR interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
TRHR inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.