A pyrrolizidine alkaloid and a toxic plant constituent that poisons livestock and humans through the ingestion of contaminated grains and other foods. The alkaloid causes pulmonary artery hypertension, right ventricular hypertrophy, and pathological changes in the pulmonary vasculature. Significant attenuation of the cardiopulmonary changes are noted after oral magnesium treatment.
Monocrotaline has been studied across 19 research domains including 🫁 Respiratory, ❤️ Cardiovascular, 🏋️ Muscle & Hypertrophy, 🫁 Liver & Detox, 😴 Sleep. The primary research focus is 🫁 Respiratory with 73% of studies addressing this area.
The following compounds share molecular targets with Monocrotaline, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.
This evidence profile for Monocrotaline is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.
Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.