Question 1

What compounds affect the ROS and RNS production in phagocytes pathway?

Accepted Answer

24 compounds in the BiohacksAI corpus have documented interactions with genes in the ROS and RNS production in phagocytes pathway (Reactome ID: R-HSA-1222556). These compounds target 7 genes within this pathway.

Question 2

What genes are in the ROS and RNS production in phagocytes pathway?

Accepted Answer

The ROS and RNS production in phagocytes pathway involves 7 genes. Key genes include: ATP6V1B2, CYBB, MPO, NCF1, NOS1, NOS2, NOS3.

#	Compound	Targets Hit	Studies
1	Nitroarginine	—	300
2	Arginine	—	300
3	Arginine	—	300
4	NG-Nitroarginine Methyl Ester	—	238
5	Apigenin 5,7,4'-trihydroxy-flavone,	—	300
6	Guanethidine	—	300
7	Quercetin	—	300
8	Metoclopramide	—	297
9	Isoniazid Antibacterial agent used primarily as	—	299
10	Kaempferols	—	300
11	Melatonin	—	297
12	Dapsone	—	297
13	Tryptophan	—	300
14	alyssin [Supplementary Concept]	—	300
15	Catechin	—	300
16	sesamol	—	293
17	Luteolin 5,7,3',4'-tetrahydroxy-flavone,	—	150
18	chrysin	—	300
19	celastrol	—	300
20	Naloxone	—	299
21	Methylene Blue	—	200
22	indirubin	—	300
23	Loxapine	—	30
24	Enoxacin	—	299

BiohacksAI

ROS and RNS production in phagocytes

Genes in this Pathway

Compounds Affecting ROS and RNS production in phagocytes

About the ROS and RNS production in phagocytes Pathway