BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
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Melatonin

A biogenic amine that is found in animals and plants. In mammals, melatonin is produced by the PINEAL GLAND. Its secretion increases in darkness and decreases during exposure to light. Melatonin is implicated in the regulation of SLEEP, mood, and REPRODUCTION. Melatonin is also an effective antioxidant.

495+ PubMed studies analyzed · 49 RCTs · Evidence Score: 61.3

Research Domains

Melatonin has been studied across 23 research domains including 😴 Sleep, 🔬 Inflammation, 🧘 Stress & Anxiety, 🔬 Oncology, ⏳ Longevity & Aging. The primary research focus is 😴 Sleep with 97% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Melatonin, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

propyl
8 shared targets
Methoxsalen
9 shared targets
Isoniazid
7 shared targets
Picloram
6 shared targets
Propanil
7 shared targets
Ethanolamine
7 shared targets
Linezolid
7 shared targets
Phenytoin
7 shared targets
Betamethasone
7 shared targets
Diuron
6 shared targets
Loading evidence profile...

This evidence profile for Melatonin is generated deterministically from 495 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.