Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB

Q: What compounds affect the Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB pathway?

38 compounds in the BiohacksAI corpus have documented interactions with genes in the Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB pathway (Reactome ID: R-HSA-141333). These compounds target 2 genes within this pathway.

REACTOME PATHWAY

Reactome: R-HSA-1413332 genes38 compounds

The Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB pathway (Reactome ID: R-HSA-141333) involves 2 genes and is affected by 38 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.

Genes in this Pathway

MAOA MAOB

Compounds Affecting Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB

#	Compound	Targets Hit	Studies
1	Iproniazid	—	300
2	Moclobemide	—	299
3	Apigenin 5,7,4'-trihydroxy-flavone,	—	300
4	Phenelzine	—	297
5	Genistein	—	300
6	Idazoxan	—	300
7	hispidol	—	13
8	Linezolid	—	298
9	Vitamin K 3	—	300
10	chrysin	—	300
11	auraptene	—	148
12	Emodin Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as	—	300
13	Fentanyl	—	300
14	Rilmenidine Oxazole derivative that acts as	—	300
15	Harmine Alkaloid isolated from seeds of PEGANUM HARMALA; ZYGOPHYLLACEAE. It is identical to banisterine, or telepathine, from Banisteria caapi and is	—	300
16	Quercetin	—	300
17	Luteolin 5,7,3',4'-tetrahydroxy-flavone,	—	150
18	Harmaline	—	300
19	1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine	—	300
20	Methylene Blue	—	200
21	myricetin-3-O-galactopyranoside [Supplementary Concept]	—	300
22	plumbagin [Supplementary Concept]	—	300
23	Sirolimus	—	300
24	Rutin	—	300
25	Aripiprazole	—	298
26	Famotidine	—	296
27	Guanabenz	—	298
28	Guanfacine	—	294
29	juglone hydroxylase [Supplementary Concept] catalyzes	—	279
30	Lynestrenol	—	299
31	1-(5,8-dihydro-1,4-dihydroxy-5,8-dioxo-2-naphthyl)-4-methylpent-3-en-1-yl cinnamate [Supplementary Concept]	—	54
32	pentamidine	—	299
33	Sorafenib	—	300
34	Pioglitazone	—	297
35	Farnesol	—	300
36	Zonisamide	—	297
37	Troglitazone	—	299
38	Resveratrol	—	298

About the Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB Pathway

The Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB pathway is catalogued in Reactome (ID: R-HSA-141333) and involves 2 genes. In the BiohacksAI corpus, 38 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include MAOA, MAOB.