Question 1

What compounds affect the Translocation of SLC2A4 (GLUT4) to the plasma membrane pathway?

Accepted Answer

25 compounds in the BiohacksAI corpus have documented interactions with genes in the Translocation of SLC2A4 (GLUT4) to the plasma membrane pathway (Reactome ID: R-HSA-1445148). These compounds target 26 genes within this pathway.

Question 2

What genes are in the Translocation of SLC2A4 (GLUT4) to the plasma membrane pathway?

Accepted Answer

The Translocation of SLC2A4 (GLUT4) to the plasma membrane pathway involves 26 genes. Key genes include: PRKAA2, PRKAB1, PRKAB2, PRKAG1, PRKAG2, PRKAG3, SLC2A4, TUBA1A, TUBA1B, TUBA1C.

#	Compound	Targets Hit	Studies
1	Colchicine	—	300
2	Nocodazole Nocodazole is	—	215
3	Vincristine	—	299
4	Noscapine	—	300
5	Podophyllotoxin	—	14
6	Demecolcine	—	246
7	Maytansine	—	300
8	vinblastine sulfate	—	81
9	Vorinostat	—	299
10	Adenosine Monophosphate Adenine nucleotide containing	—	300
11	Proguanil	—	299
12	Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone	—	76
13	Niclosamide	—	299
14	Berberine	—	300
15	Ursolic Acid	—	300
16	Antimycin	—	300
17	Oleanolic Acid	—	300
18	Rotenone	—	300
19	Metformin	—	1,000
20	Quercetin	—	300
21	Kaempferols	—	300
22	Rutin	—	300
23	Idarubicin	—	299
24	Masoprocol	—	300
25	Glucose	—	294

BiohacksAI

Translocation of SLC2A4 (GLUT4) to the plasma membrane

Genes in this Pathway

Compounds Affecting Translocation of SLC2A4 (GLUT4) to the plasma membrane

About the Translocation of SLC2A4 (GLUT4) to the plasma membrane Pathway