STING mediated induction of host immune responses
REACTOME PATHWAYThe STING mediated induction of host immune responses pathway (Reactome ID: R-HSA-1834941) involves 3 genes and is affected by 18 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting STING mediated induction of host immune responses
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | amlexanox | — | 96 |
| 2 | Suramin | — | 300 |
| 3 | myricetin-3-O-galactopyranoside [Supplementary Concept] | — | 300 |
| 4 | Aurintricarboxylic Acid | — | 184 |
| 5 | Idarubicin | — | 299 |
| 6 | Epirubicin | — | 300 |
| 7 | Daunorubicin | — | 298 |
| 8 | Hexachlorophene | — | 300 |
| 9 | Nisoldipine | — | 297 |
| 10 | egcg | — | 300 |
| 11 | Dequalinium | — | 136 |
| 12 | Disulfiram | — | 297 |
| 13 | Folic Acid | — | 296 |
| 14 | piromidic acid | — | 64 |
| 15 | Riboflavin Nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables. | — | 297 |
| 16 | Axitinib | — | 298 |
| 17 | Crizotinib | — | 298 |
| 18 | Wortmannin | — | 300 |
About the STING mediated induction of host immune responses Pathway
The STING mediated induction of host immune responses pathway is catalogued in Reactome (ID: R-HSA-1834941) and involves 3 genes. In the BiohacksAI corpus, 18 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include CGAS, PRKDC, TBK1.