Tachykinin receptors bind tachykinins
REACTOME PATHWAYThe Tachykinin receptors bind tachykinins pathway (Reactome ID: R-HSA-380095) involves 3 genes and is affected by 15 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Tachykinin receptors bind tachykinins
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Substance P | — | 299 |
| 2 | Neurokinin | — | 300 |
| 3 | Neurokinin B | — | 300 |
| 4 | Aprepitant | — | 297 |
| 5 | Eledoisin | — | 300 |
| 6 | Kassinin Dodecapeptide tachykinin found in | — | 182 |
| 7 | Amoxapine | — | 259 |
| 8 | Aripiprazole | — | 298 |
| 9 | Astemizole Antihistamine drug now withdrawn from | — | 280 |
| 10 | Carvedilol | — | 296 |
| 11 | Dextromethorphan Methyl analog of DEXTRORPHAN that shows high affinity binding to several regions of | — | 296 |
| 12 | Fidaxomicin | — | 295 |
| 13 | neurokinin 1 receptor antagonists | — | 249 |
| 14 | Ritonavir | — | 298 |
| 15 | Trazodone | — | 297 |
About the Tachykinin receptors bind tachykinins Pathway
The Tachykinin receptors bind tachykinins pathway is catalogued in Reactome (ID: R-HSA-380095) and involves 3 genes. In the BiohacksAI corpus, 15 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include TACR1, TACR2, TACR3.