What compounds affect the Lysosome Vesicle Biogenesis pathway?

33 compounds in the BiohacksAI corpus have documented interactions with genes in the Lysosome Vesicle Biogenesis pathway (Reactome ID: R-HSA-432720). These compounds target 3 genes within this pathway.

What genes are in the Lysosome Vesicle Biogenesis pathway?

The Lysosome Vesicle Biogenesis pathway involves 3 genes. Key genes include: APP, ARRB1, HSPA8.

Lysosome Vesicle Biogenesis

REACTOME PATHWAY

Reactome: R-HSA-4327203 genes33 compounds

The Lysosome Vesicle Biogenesis pathway (Reactome ID: R-HSA-432720) involves 3 genes and is affected by 33 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.

Genes in this Pathway

APP ARRB1 HSPA8

Compounds Affecting Lysosome Vesicle Biogenesis

#	Compound	Targets Hit	Studies
1	Resveratrol	—	298
2	Quercetin	—	300
3	egcg	—	300
4	Hesperidin	—	300
5	myricetin-3-O-galactopyranoside [Supplementary Concept]	—	300
6	Kaempferols	—	300
7	Methylene Blue	—	200
8	Luteolin 5,7,3',4'-tetrahydroxy-flavone,	—	150
9	(N-methyl-C-11)-2-(4-methylamino-phenyl)-6-hydroxybenzothiazole [Supplementary Concept] neutral analog of amyloid-binding thioflavin-T (BTA) that crosses	—	300
10	Apigenin 5,7,4'-trihydroxy-flavone,	—	300
11	caffeic acid	—	300
12	Vitamin	—	295
13	2-Methoxyestradiol	—	300
14	arctigenin-4-O-(3''-O-acetyl-beta-D-glucoside) [Supplementary Concept] isolated from	—	300
15	Cladribine	—	297
16	Digitoxin	—	300
17	Digoxin	—	299
18	Disulfiram	—	297
19	Edetic Acid	—	24
20	Catechin	—	300
21	Vanillic Acid	—	300
22	Ouabain	—	300
23	Podophyllotoxin	—	14
24	Quinic Acid	—	218
25	Retinaldehyde	—	300
26	streptonigrin	—	299
27	Trifluridine	—	295
28	aniracetam	—	110
29	Nadolol	—	297
30	Nicardipine	—	94
31	Adenosine Diphosphate Adenosine 5'-(trihydrogen diphosphate).	—	300
32	Hexachlorophene	—	300
33	Ergosterol	—	300

About the Lysosome Vesicle Biogenesis Pathway

The Lysosome Vesicle Biogenesis pathway is catalogued in Reactome (ID: R-HSA-432720) and involves 3 genes. In the BiohacksAI corpus, 33 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include APP, ARRB1, HSPA8.