BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
BiohacksAI is an evolving scientific literature platform. New compounds and evidence are indexed continuously.
B
○

2 Methoxyestradiol

A metabolite of estradiol that lacks estrogenic activity and inhibits TUBULIN polymerization. It has antineoplastic properties, including inhibition of angiogenesis and induction of APOPTOSIS.

300+ PubMed studies analyzed · Evidence Score: 39.6

Research Domains

2 Methoxyestradiol has been studied across 22 research domains including 🔬 Oncology, 🧬 Hormones, 🔬 Inflammation, ❤️ Cardiovascular, 🫁 Liver & Detox. The primary research focus is 🔬 Oncology with 59% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with 2 Methoxyestradiol, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

darapladib
12 shared targets
Ticagrelor
10 shared targets
propionylpromazine
12 shared targets
Thiorphan
7 shared targets
Estrone
10 shared targets
Demeclocycline
6 shared targets
Benzethonium
11 shared targets
tyrphostin
14 shared targets
Vemurafenib
11 shared targets
tyrphostin
12 shared targets
Loading evidence profile...

This evidence profile for 2 Methoxyestradiol is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.