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Trifluridine

An antiviral derivative of THYMIDINE used mainly in the treatment of primary keratoconjunctivitis and recurrent epithelial keratitis due to HERPES SIMPLEX virus. (From Martindale, The Extra Pharmacopoeia, 30th ed, p557)

295+ PubMed studies analyzed · 23 RCTs · Evidence Score: 55.3

Research Domains

Trifluridine has been studied across 9 research domains including 🔬 Oncology, 🧠 Neuroprotection, ⏳ Longevity & Aging, 🛡️ Immunity, 🫁 Liver & Detox. The primary research focus is 🔬 Oncology with 68% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Trifluridine, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

Cytarabine
16 shared targets
Ciclopirox
16 shared targets
Cladribine
16 shared targets
Melphalan
15 shared targets
Azacitidine
18 shared targets
Azacitidine
18 shared targets
Proscillaridin
10 shared targets
Thioinosine
10 shared targets
Clofarabine
13 shared targets
Methotrexate
19 shared targets
Loading evidence profile...

This evidence profile for Trifluridine is generated deterministically from 295 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.