Question 1

What compounds affect the Intra-Golgi and retrograde Golgi-to-ER traffic pathway?

Accepted Answer

34 compounds in the BiohacksAI corpus have documented interactions with genes in the Intra-Golgi and retrograde Golgi-to-ER traffic pathway (Reactome ID: R-HSA-6811442). These compounds target 26 genes within this pathway.

Question 2

What genes are in the Intra-Golgi and retrograde Golgi-to-ER traffic pathway?

Accepted Answer

The Intra-Golgi and retrograde Golgi-to-ER traffic pathway involves 26 genes. Key genes include: CYTH2, GALNT1, GALNT2, KIFC1, MAN2A1, PAFAH1B2, PAFAH1B3, RAB9A, RACGAP1, TUBA1A.

#	Compound	Targets Hit	Studies
1	Colchicine	—	300
2	Nocodazole Nocodazole is	—	215
3	Vincristine	—	299
4	Noscapine	—	300
5	Podophyllotoxin	—	14
6	Demecolcine	—	246
7	Maytansine	—	300
8	vinblastine sulfate	—	81
9	Vorinostat	—	299
10	Pueraria	—	300
11	Kaempferols	—	300
12	Luteolin 5,7,3',4'-tetrahydroxy-flavone,	—	150
13	myricetin-3-O-galactopyranoside [Supplementary Concept]	—	300
14	Ethidium	—	300
15	Oxytetracycline	—	300
16	urolithin d	—	2
17	Genistein	—	300
18	pterostilbene	—	299
19	amlexanox	—	96
20	kenpaullone	—	8
21	Leflunomide	—	297
22	Niclosamide	—	299
23	pd98059	—	7
24	Phenelzine	—	297
25	Riluzole	—	298
26	tyrphostin ag 1295	—	1
27	Nadolol	—	297
28	Myristic Acid	—	300
29	Catechin	—	300
30	Equilin	—	216
31	Adenosine Diphosphate Adenosine 5'-(trihydrogen diphosphate).	—	300
32	Adenosine Triphosphate	—	300
33	Clotrimazole	—	296
34	Swainsonine	—	300

BiohacksAI

Intra-Golgi and retrograde Golgi-to-ER traffic

Genes in this Pathway

Compounds Affecting Intra-Golgi and retrograde Golgi-to-ER traffic

About the Intra-Golgi and retrograde Golgi-to-ER traffic Pathway