Question 1

What compounds affect the Protein ubiquitination pathway?

Accepted Answer

23 compounds in the BiohacksAI corpus have documented interactions with genes in the Protein ubiquitination pathway (Reactome ID: R-HSA-8852135). These compounds target 7 genes within this pathway.

Question 2

What genes are in the Protein ubiquitination pathway?

Accepted Answer

The Protein ubiquitination pathway involves 7 genes. Key genes include: HLA-A, PCNA, PRKDC, UBE2N, USP5, USP7, VCP.

#	Compound	Targets Hit	Studies
1	Astemizole Antihistamine drug now withdrawn from	—	280
2	naringin	—	300
3	Chlorhexidine	—	299
4	Perphenazine	—	297
5	Sphingosine	—	300
6	Resveratrol	—	298
7	Sertraline	—	1,000
8	Canrenone	—	300
9	Thioridazine	—	35
10	Hexachlorophene	—	300
11	Oxytetracycline	—	300
12	egcg	—	300
13	Clotrimazole	—	296
14	Demeclocycline	—	5
15	Edaravone	—	298
16	alpha-Linolenic Acid	—	300
17	Luteolin 5,7,3',4'-tetrahydroxy-flavone,	—	150
18	Quercetin	—	300
19	celastrol	—	300
20	Oleanolic Acid	—	300
21	Triiodothyronine	—	300
22	Vemurafenib	—	298
23	Wortmannin	—	300

BiohacksAI

Protein ubiquitination

Genes in this Pathway

Compounds Affecting Protein ubiquitination

About the Protein ubiquitination Pathway