Rab regulation of trafficking
REACTOME PATHWAYThe Rab regulation of trafficking pathway (Reactome ID: R-HSA-9007101) involves 6 genes and is affected by 19 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Rab regulation of trafficking
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Pueraria | — | 300 |
| 2 | Genistein | — | 300 |
| 3 | pterostilbene | — | 299 |
| 4 | amlexanox | — | 96 |
| 5 | kenpaullone | — | 8 |
| 6 | Leflunomide | — | 297 |
| 7 | Niclosamide | — | 299 |
| 8 | pd98059 | — | 7 |
| 9 | Phenelzine | — | 297 |
| 10 | Riluzole | — | 298 |
| 11 | tyrphostin ag 1295 | — | 1 |
| 12 | Biotin | — | 297 |
| 13 | myricetin-3-O-galactopyranoside [Supplementary Concept] | — | 300 |
| 14 | Oxytetracycline | — | 300 |
| 15 | Guanosine Diphosphate | — | 300 |
| 16 | Guanosine Triphosphate Guanosine 5'-(tetrahydrogen triphosphate). | — | 300 |
| 17 | Crizotinib | — | 298 |
| 18 | hydroxyfasudil [Supplementary Concept] | — | 11 |
| 19 | Novobiocin | — | 300 |
About the Rab regulation of trafficking Pathway
The Rab regulation of trafficking pathway is catalogued in Reactome (ID: R-HSA-9007101) and involves 6 genes. In the BiohacksAI corpus, 19 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include AKT3, MAP1LC3B, RAB7A, RAB9A, RIN1.