Question 1

What compounds affect the Activation of AMPK downstream of NMDARs pathway?

Accepted Answer

25 compounds in the BiohacksAI corpus have documented interactions with genes in the Activation of AMPK downstream of NMDARs pathway (Reactome ID: R-HSA-9619483). These compounds target 25 genes within this pathway.

Question 2

What genes are in the Activation of AMPK downstream of NMDARs pathway?

Accepted Answer

The Activation of AMPK downstream of NMDARs pathway involves 25 genes. Key genes include: CAMKK2, PRKAA1, PRKAA2, PRKAB1, PRKAB2, PRKAG1, PRKAG2, PRKAG3, TUBA1A, TUBA1B.

#	Compound	Targets Hit	Studies
1	Colchicine	—	300
2	Nocodazole Nocodazole is	—	215
3	Vincristine	—	299
4	Noscapine	—	300
5	Podophyllotoxin	—	14
6	Demecolcine	—	246
7	Maytansine	—	300
8	vinblastine sulfate	—	81
9	Vorinostat	—	299
10	Adenosine Monophosphate Adenine nucleotide containing	—	300
11	Proguanil	—	299
12	Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone	—	76
13	Niclosamide	—	299
14	Berberine	—	300
15	Ursolic Acid	—	300
16	Antimycin	—	300
17	Oleanolic Acid	—	300
18	Rotenone	—	300
19	Metformin	—	1,000
20	Crizotinib	—	298
21	Quercetin	—	300
22	Kaempferols	—	300
23	Rutin	—	300
24	sp600125	—	117
25	Axitinib	—	298

BiohacksAI

Activation of AMPK downstream of NMDARs

Genes in this Pathway

Compounds Affecting Activation of AMPK downstream of NMDARs

About the Activation of AMPK downstream of NMDARs Pathway