Acetylcholine inhibits contraction of outer hair cells

Q: What compounds affect the Acetylcholine inhibits contraction of outer hair cells pathway?

38 compounds in the BiohacksAI corpus have documented interactions with genes in the Acetylcholine inhibits contraction of outer hair cells pathway (Reactome ID: R-HSA-9667769). These compounds target 2 genes within this pathway.

REACTOME PATHWAY

Reactome: R-HSA-96677692 genes38 compounds

The Acetylcholine inhibits contraction of outer hair cells pathway (Reactome ID: R-HSA-9667769) involves 2 genes and is affected by 38 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.

Genes in this Pathway

KCNMA1 KCNMB1

Compounds Affecting Acetylcholine inhibits contraction of outer hair cells

#	Compound	Targets Hit	Studies
1	Budesonide	—	1,000
2	pterostilbene	—	299
3	Carvedilol	—	296
4	Fluocinolone Acetonide	—	295
5	Latanoprost	—	299
6	Nisoldipine	—	297
7	Promethazine	—	121
8	Thioridazine	—	35
9	Amoxapine	—	259
10	nafadotride	—	14
11	3',4'-didemethylnobiletin [Supplementary Concept]	—	300
12	Nortriptyline	—	28
13	Perphenazine	—	297
14	Ritonavir	—	298
15	Resveratrol	—	298
16	Ethylestrenol	—	70
17	Ezetimibe	—	296
18	Glyburide	—	298
19	Irbesartan	—	298
20	Oxaprozin	—	181
21	Thyroxine	—	994
22	Simvastatin	—	1,000
23	Calcitriol	—	300
24	Chlorpheniramine	—	157
25	Desoximetasone	—	86
26	Disulfiram	—	297
27	Etodolac	—	296
28	Levonorgestrel	—	292
29	Norgestrel	—	300
30	Oxcarbazepine	—	296
31	Thyroxine	—	300
32	Ursodeoxycholic Acid	—	298
33	Flutamide	—	298
34	Imatinib Mesylate	—	300
35	Lovastatin	—	300
36	L 741519 [Supplementary Concept]	—	25
37	Torsemide	—	245
38	Vecuronium Bromide Monoquaternary homolog of PANCURONIUM.	—	298

About the Acetylcholine inhibits contraction of outer hair cells Pathway

The Acetylcholine inhibits contraction of outer hair cells pathway is catalogued in Reactome (ID: R-HSA-9667769) and involves 2 genes. In the BiohacksAI corpus, 38 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include KCNMA1, KCNMB1.