What compounds target ADORA3?

BiohacksAI has identified 42 compounds that interact with ADORA3 (adenosine A3 receptor). Top compounds include: 2-Chloroadenosine 2-Chloroadenosine., Adenosine, Benzethonium Bactericidal cationic quaternary ammonium surfactant used as, Bromocriptine, Troglitazone. Each compound is ranked by evidence score derived from PubMed bioassay confidence and assay count.

What is ADORA3 (adenosine A3 receptor)?

ADORA3 is adenosine A3 receptor. It is a molecular target for 42 compounds documented in PubMed bioassay data. UniProt ID: P0DMS8. NCBI Gene ID: 140.

ADORA3

MOLECULAR TARGET

adenosine A3 receptor

UniProt: P0DMS8 NCBI Gene: 14042 compounds

ADORA3 (adenosine A3 receptor) is targeted by 42 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).

Compounds Targeting ADORA3

Ranked by bioassay confidence score (PubChem active assay count × evidence quality).

#	Compound	Confidence	Active Assays
1	2-Chloroadenosine 2-Chloroadenosine.	2.08	7
2	Adenosine	1.10	2
3	Benzethonium Bactericidal cationic quaternary ammonium surfactant used as	1.10	2
4	Bromocriptine	1.10	2
5	Troglitazone	1.10	2
6	Kinetin	0.69	1
7	Quercetin	0.69	1
8	same	0.69	1
9	Simvastatin	0.69	1
10	Vitamin K 2	0.69	1
11	Aripiprazole	0.69	1
12	Axitinib	0.69	1
13	Calcitriol	0.69	1
14	candesartan cilexetil [Supplementary Concept]	0.69	1
15	Celecoxib	0.69	1
16	Chlorhexidine	0.69	1
17	cinacalcet	0.69	1
18	Clotrimazole	0.69	1
19	Crizotinib	0.69	1
20	Cyclizine	0.69	1
21	Dequalinium	0.69	1
22	Desogestrel	0.69	1
23	Disulfiram	0.69	1
24	Ethynodiol Diacetate	0.69	1
25	Ezetimibe	0.69	1
26	Flunarizine Flunarizine is	0.69	1
27	Fluspirilene	0.69	1
28	Hexachlorophene	0.69	1
29	Loratadine	0.69	1
30	Meclizine	0.69	1
31	Mometasone Furoate	0.69	1
32	Nisoldipine	0.69	1
33	Norethindrone Acetate Acetate ester of norethindrone that is used as	0.69	1
34	Oxymetholone	0.69	1
35	Pentostatin	0.69	1
36	Rimonabant	0.69	1
37	s adenosylmethionine	0.69	1
38	Sorafenib	0.69	1
39	Suramin	0.69	1
40	Thiabendazole 2-Substituted benzimidazole first introduced in 1962. It is active against	0.69	1
41	Thiethylperazine	0.69	1
42	Ticagrelor	0.69	1

About ADORA3 as a Drug Target

ADORA3 (adenosine A3 receptor) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 42 compounds with documented ADORA3 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.

ADORA3 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.