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Cyclizine

A histamine H1 antagonist given by mouth or parenterally for the control of postoperative and drug-induced vomiting and in motion sickness. (From Martindale, The Extra Pharmacopoeia, 30th ed, p935)

251+ PubMed studies analyzed · 25 RCTs · Evidence Score: 44.3

Research Domains

Cyclizine has been studied across 15 research domains including 💊 Pain, 😴 Sleep, 🧠 Focus & Attention, 🔬 Oncology, 🫁 Liver & Detox. The primary research focus is 💊 Pain with 11% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Cyclizine, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

Dimenhydrinate
8 shared targets
Cinnarizine
13 shared targets
Oxymetazoline
8 shared targets
Trazodone
9 shared targets
Thiethylperazine
7 shared targets
Quetiapine
11 shared targets
Promethazine
13 shared targets
Maprotiline
13 shared targets
Labetalol
7 shared targets
Dimethindene
5 shared targets
Loading evidence profile...

This evidence profile for Cyclizine is generated deterministically from 251 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.