RGS4
MOLECULAR TARGETregulator of G protein signaling 4
RGS4 (regulator of G protein signaling 4) is targeted by 30 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting RGS4
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | 2-Chloroadenosine 2-Chloroadenosine. | 1.39 | 3 |
| 2 | Aripiprazole | 1.10 | 2 |
| 3 | Zearalenone (S-(E))-3,4,5,6,8,10-Hexahydro-14,16-dihydroxy-3-methyl-1H-2-benzoxacyclotetradec in-1,7(8H)-dione. | 1.10 | 2 |
| 4 | egcg | 0.69 | 1 |
| 5 | Methylene Blue | 0.69 | 1 |
| 6 | Alprostadil | 0.69 | 1 |
| 7 | Hyoscyamine | 0.69 | 1 |
| 8 | Aurintricarboxylic Acid | 0.69 | 1 |
| 9 | Calcimycin | 0.69 | 1 |
| 10 | Cisplatin | 0.69 | 1 |
| 11 | daph | 0.69 | 1 |
| 12 | Dequalinium | 0.69 | 1 |
| 13 | Diamide | 0.69 | 1 |
| 14 | Digoxin | 0.69 | 1 |
| 15 | Disulfiram | 0.69 | 1 |
| 16 | hydroxyindoleacetic acid | 0.69 | 1 |
| 17 | Iodoacetamide | 0.69 | 1 |
| 18 | Leukotriene D4 | 0.69 | 1 |
| 19 | Methyldopa | 0.69 | 1 |
| 20 | Methylergonovine | 0.69 | 1 |
| 21 | Methysergide | 0.69 | 1 |
| 22 | ns398 | 0.69 | 1 |
| 23 | piceatannol | 0.69 | 1 |
| 24 | Pilocarpine | 0.69 | 1 |
| 25 | Propantheline | 0.69 | 1 |
| 26 | Nitroprusside | 0.69 | 1 |
| 27 | triflupromazine hydrochloride | 0.69 | 1 |
| 28 | tyrphostin 9 | 0.69 | 1 |
| 29 | Uridine Monophosphate 5'-Uridylic acid. | 0.69 | 1 |
| 30 | ziprasidone hydrochloride monohydrate | 0.69 | 1 |
About RGS4 as a Drug Target
RGS4 (regulator of G protein signaling 4) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 30 compounds with documented RGS4 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
RGS4 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.