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Compounds That Target AAK1

AP2 associated kinase 1 · 106 compounds in BiohacksAI corpus

AAK1 (AP2 associated kinase 1) is a biological target with 106 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into AAK1 modulation for therapeutic and biohacking applications.

All 50 Compounds — Ranked by Evidence
1
Erlotinib
5.55
confidence
2
Alvocidib
4.52
confidence
3
Tozasertib
4.33
confidence
4
Ruxolitinib
4.23
confidence
5
Palbociclib
4.22
confidence
6
Bosutinib
4.08
confidence
7
Bi 2536
4.01
confidence
8
Midostaurin
3.85
confidence
9
Pazopanib
3.69
confidence
10
Abemaciclib
3.66
confidence
11
Nintedanib
3.61
confidence
12
Baricitinib
3.56
confidence
13
Pelitinib
3.50
confidence
14
Tae 684
3.43
confidence
15
Pexidartinib
3.43
confidence
16
Fedratinib
3.40
confidence
17
Gilteritinib
3.40
confidence
18
Sp 600125
3.22
confidence
19
Dovitinib
3.09
confidence
20
Jnj 7706621
3.09
confidence
21
At 9283
3.09
confidence
22
Upadacitinib
3.09
confidence
23
Selumetinib
3.09
confidence
24
Lestaurtinib
3.04
confidence
25
Pacritinib
3.04
confidence
26
Filgotinib
3.04
confidence
27
Pf 03758309
3.00
confidence
28
Ruboxistaurin
2.94
confidence
29
Defosbarasertib
2.89
confidence
30
Momelotinib
2.89
confidence
31
Orantinib
2.89
confidence
32
R 406
2.83
confidence
33
K 252a
2.83
confidence
34
Milciclib
2.77
confidence
35
Pha 665752
2.71
confidence
36
Azd 5438
2.71
confidence
37
Kw 2449
2.64
confidence
38
Azd 7762
2.30
confidence
39
Su 014813
2.20
confidence
40
Decernotinib
2.20
confidence
41
Y 39983
2.20
confidence
42
Cyc 116
2.08
confidence
43
Enzastaurin
2.08
confidence
44
Tg100 115
2.08
confidence
45
Asp 3026
2.08
confidence
46
Mk 2461
2.08
confidence
47
Ravoxertinib
2.08
confidence
48
Gsk 1059615
1.95
confidence
49
Whi P131
1.95
confidence
50
Pf 03814735
1.79
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for AAK1 (AP2 associated kinase 1). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: AAK1 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.