Identifies research gaps — substances where published evidence suggests development opportunity but clinical validation is missing. Pure deterministic math across 6 signal dimensions, no AI interpretation.
🧬Longevity Gap — Strong DrugAge model organism longevity signal without corresponding human clinical trials.
🎯Domain Gap — Substance researched in a specific domain but the research is primarily preclinical or in-vitro — human clinical evidence is missing in that domain.
🔀Spillover — FDA-approved substance with active research in domains outside its approved indications.
📈Accelerating — Publication rate rapidly increasing with limited or no regulatory coverage.
🛡️Repurposing — Known safety profile with active off-label domain research — repurposing candidates.
🔬Multi-Species — Lifespan extension reproduced across 3+ model organism species with limited human evidence.