Compounds That Target ABCB1

ATP binding cassette subfamily B member 1 · 205 compounds in BiohacksAI corpus

ABCB1 (ATP binding cassette subfamily B member 1) is an ATP-binding cassette (ABC) transporter involved in the active efflux of compounds from cells. ABC transporters are key mediators of multidrug resistance and compound bioavailability. The 205 compounds listed have evidence of ABCB1 interaction from BindingDB binding assays.

View ABCB1 target page →UniProt: P08183 ↗

Most Studied Compounds for ABCB1

Quinidine

298+

studies

Reserpine

297+

studies

All 50 Compounds — Ranked by Evidence

Paclitaxel

7.17

confidence

Combretastatin A4

6.30

confidence

Tamoxifen

5.88

confidence

Doxorubicin Hydrochloride

5.71

confidence

Gefitinib

5.67

confidence

Imatinib

5.47

confidence

Epigalocatechin Gallate

5.40

confidence

Etravirine

5.05

confidence

Saquinavir

4.98

confidence

Diltiazem

4.74

confidence

Alpha Naphthoflavone

4.67

confidence

Omeprazole

4.64

confidence

Lopinavir

4.64

confidence

Propafenone

4.53

confidence

Amiodarone

4.51

confidence

Nelfinavir

4.51

confidence

Flavone

4.34

confidence

Galangin

4.30

confidence

Nicardipine

4.28

confidence

Trifluoperazine

4.25

confidence

Atazanavir

4.23

confidence

Tariquidar

4.20

confidence

Ceritinib

4.19

confidence

Doramapimod

4.06

confidence

7 Hydroxyflavone

4.01

confidence

Midostaurin

3.85

confidence

Licoagrochacone A

3.83

confidence

Flavonol

3.64

confidence

Nintedanib

3.61

confidence

Sertindole

3.58

confidence

Elacridar

3.56

confidence

Fumitremorgin

3.43

confidence

Osthole

3.40

confidence

Tangeretin

3.40

confidence

Kaempferide

3.37

confidence

Pentosalen

3.37

confidence

Scutellarin

3.18

confidence

Techtochrysin

3.18

confidence

Retusin

3.14

confidence

Sinensetin

2.94

confidence

Reserpine

297+

studies

2.83

confidence

Linsitinib

2.64

confidence

Ebastine

2.64

confidence

Niguldipine

2.56

confidence

Ayanin

2.56

confidence

Quinidine

298+

studies

2.48

confidence

Pentamethylquercetin

2.40

confidence

Bms 754807

2.30

confidence

S Verapamil

2.30

confidence

6 Methoxyflavone

2.30

confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for ABCB1 (ATP binding cassette subfamily B member 1). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: ABCB1 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.