Compounds That Target ABCG2

ATP binding cassette subfamily G member 2 (JR blood group) · 188 compounds in BiohacksAI corpus

ABCG2 (ATP binding cassette subfamily G member 2 (JR blood group)) is an ATP-binding cassette (ABC) transporter involved in the active efflux of compounds from cells. ABC transporters are key mediators of multidrug resistance and compound bioavailability. The 188 compounds listed have evidence of ABCG2 interaction from BindingDB binding assays.

View ABCG2 target page →UniProt: Q9UNQ0 ↗

Most Studied Compounds for ABCG2

Licochalcone A

267+

studies

All 50 Compounds — Ranked by Evidence

Efavirenz

5.81

confidence

Gefitinib

5.67

confidence

Erlotinib

5.55

confidence

Imatinib

5.47

confidence

Nifedipine

5.34

confidence

Etravirine

5.05

confidence

Saquinavir

4.98

confidence

Posaconazole

4.90

confidence

Lapatinib

4.84

confidence

Sirolimus

4.82

confidence

Atovaquone

4.80

confidence

Alpha Naphthoflavone

4.67

confidence

Omeprazole

4.64

confidence

Lopinavir

4.64

confidence

Thioridazine

4.52

confidence

Nelfinavir

4.51

confidence

Tacrolimus Anhydrous

4.45

confidence

Flavone

4.34

confidence

Vandetanib

4.30

confidence

Nimodipine

4.29

confidence

Telmisartan

4.29

confidence

Morin

4.28

confidence

Nicardipine

4.28

confidence

Sr Mefloquine

4.28

confidence

Ponatinib

4.26

confidence

Atazanavir

4.23

confidence

Tariquidar

4.20

confidence

Rilpivirine

4.20

confidence

Nilotinib

4.17

confidence

Benzbromarone

4.13

confidence

Bosutinib

4.08

confidence

Dipyridamole

4.03

confidence

Vismodegib

4.03

confidence

Lansoprazole

4.01

confidence

Namodenoson

3.95

confidence

Mk 571

3.87

confidence

Midostaurin

3.85

confidence

Licoagrochacone A

3.83

confidence

Regorafenib

3.56

confidence

Elacridar

3.56

confidence

Beta Naphthoflavone

3.50

confidence

Fumitremorgin

3.43

confidence

Tangeretin

3.40

confidence

Pantoprazole

3.37

confidence

Licochalcone A

267+

studies

3.30

confidence

Alectinib

3.18

confidence

Rabeprazole

3.18

confidence

Sq109

3.18

confidence

Techtochrysin

3.18

confidence

Retusin

3.14

confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for ABCG2 (ATP binding cassette subfamily G member 2 (JR blood group)). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: ABCG2 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.