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Compounds That Target ADAM17

ADAM metallopeptidase domain 17 · 85 compounds in BiohacksAI corpus

ADAM17 (ADAM metallopeptidase domain 17) is a biological target with 85 documented compound interactions in the BiohacksAI corpus. The compounds listed below have been identified through computational analysis of BindingDB binding assay data and PubMed literature. Each interaction is ranked by confidence score reflecting the breadth and strength of experimental evidence. This resource supports research into ADAM17 modulation for therapeutic and biohacking applications.

Most Studied Compounds for ADAM17
1.0k+
studies
500+
studies
500+
studies
499+
studies
499+
studies
300+
studies
300+
studies
199+
studies
All 50 Compounds — Ranked by Evidence
1
Cgs 27023a
3.76
confidence
2
Marimastat
3.47
confidence
3
Ilomastat
3.40
confidence
4
Prinomastat
2.94
confidence
5
Cts 1027
2.64
confidence
6
Batimastat
2.48
confidence
7
Ro 319790
1.79
confidence
197+
studies
1.10
confidence
9
Achyranthes Bidentata
1.00
confidence
10
Agastache Rugosa
1.00
confidence
500+
studies
1.00
confidence
12
Aloe Vera
1.00
confidence
13
Bupleurum Chinense
1.00
confidence
499+
studies
1.00
confidence
499+
studies
1.00
confidence
16
Gastrodia Elata
1.00
confidence
17
Glycine Max
1.00
confidence
18
Lithospermum Erythrorhizon
1.00
confidence
19
Lonicera Japonica
1.00
confidence
20
Morus Alba
1.00
confidence
300+
studies
1.00
confidence
22
Panax Notoginseng
1.00
confidence
23
Perilla Frutescens
1.00
confidence
24
Polygonum Cuspidatum
1.00
confidence
25
Prunella Vulgaris
1.00
confidence
26
Prunus Armeniaca
1.00
confidence
500+
studies
1.00
confidence
28
Salvia Miltiorrhiza
1.00
confidence
29
Schisandra Chinensis
1.00
confidence
30
Scutellaria Baicalensis
1.00
confidence
142+
studies
1.00
confidence
32
Smilax Glabra
1.00
confidence
33
Stemona Sessilifolia
1.00
confidence
34
Taraxacum Mongolicum
1.00
confidence
35
Tussilago Farfara
1.00
confidence
498+
studies
1.00
confidence
37
Ziziphus Jujuba
1.00
confidence
300+
studies
0.69
confidence
1.0k+
studies
0.69
confidence
40
Aconitum Carmichaelii
0.50
confidence
41
Allium Fistulosum
0.50
confidence
42
Apis Mellifera
0.50
confidence
43
Arctium Lappa
0.50
confidence
199+
studies
0.50
confidence
45
Atractylodes Macrocephala
0.50
confidence
46
Aucklandia Lappa
0.50
confidence
47
Bombyx Mori
0.50
confidence
48
Carthamus Tinctorius
0.50
confidence
49
Chaenomeles Speciosa
0.50
confidence
50
Cimicifuga Heracleifolia
0.50
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for ADAM17 (ADAM metallopeptidase domain 17). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: ADAM17 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.