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BiohacksAI/Targets/AKT2/Compounds

Compounds That Target AKT2

RAC-beta serine/threonine-protein kinase · 100 compounds in BiohacksAI corpus

AKT2 (RAC-beta serine/threonine-protein kinase) is a protein kinase involved in intracellular signal transduction. Kinases phosphorylate downstream substrates to regulate cell growth, survival, and metabolism. The 100 compounds targeting AKT2 include both pharmaceutical inhibitors and natural compounds with evidence of kinase modulation, ranked by evidence strength from the BiohacksAI corpus.

View AKT2 target page →
Most Studied Compounds for AKT2
1
Allium Sativum
500+
studies
2
Zingiber Officinale
498+
studies
3
Panax Ginseng
300+
studies
4
Rubia Cordifolia
200+
studies
5
Areca Catechu
199+
studies
6
Smilax China
142+
studies
All 50 Compounds — Ranked by Evidence
1
Midostaurin
3.85
confidence
2
Lestaurtinib
3.04
confidence
3
Ruboxistaurin
2.94
confidence
4
Mk 2206
2.83
confidence
5
Capivasertib
2.77
confidence
6
Gsk 690693
2.64
confidence
7
Ipatasertib
2.20
confidence
8
A 443654
2.20
confidence
9
Gsk 269962a
2.08
confidence
10
Uprosertib
1.95
confidence
11
Borussertib
1.95
confidence
12
Afuresertib
1.79
confidence
13
Agastache Rugosa
1.00
confidence
14
Artemisia Argyi
1.00
confidence
15
Artemisia Capillaris
1.00
confidence
16
Bombyx Mori
1.00
confidence
17
Carthamus Tinctorius
1.00
confidence
18
Chaenomeles Speciosa
1.00
confidence
19
Commiphora Myrrha
1.00
confidence
20
Gentiana Macrophylla
1.00
confidence
21
Glycyrrhiza Uralensis
1.00
confidence
22
Morus Alba
1.00
confidence
23
Nelumbo Nucifera
1.00
confidence
24
Panax Ginseng
300+
studies
1.00
confidence
25
Prunus Armeniaca
1.00
confidence
26
Rehmannia Glutinosa
1.00
confidence
27
Rubia Cordifolia
200+
studies
1.00
confidence
28
Salvia Miltiorrhiza
1.00
confidence
29
Sanguisorba Officinalis
1.00
confidence
30
Scutellaria Baicalensis
1.00
confidence
31
Smilax China
142+
studies
1.00
confidence
32
Smilax Glabra
1.00
confidence
33
Trichosanthes Kirilowii
1.00
confidence
34
Vigna Umbellata
1.00
confidence
35
Zingiber Officinale
498+
studies
1.00
confidence
36
Ziziphus Jujuba
1.00
confidence
37
Achyranthes Bidentata
0.50
confidence
38
Albizia Julibrissin
0.50
confidence
39
Alisma Plantago
0.50
confidence
40
Allium Fistulosum
0.50
confidence
41
Allium Sativum
500+
studies
0.50
confidence
42
Aloe Vera
0.50
confidence
43
Anemarrhena Asphodeloides
0.50
confidence
44
Apis Mellifera
0.50
confidence
45
Aquilaria Sinensis
0.50
confidence
46
Arctium Lappa
0.50
confidence
47
Areca Catechu
199+
studies
0.50
confidence
48
Artemisia Annua
0.50
confidence
49
Belamcanda Chinensis
0.50
confidence
50
Bufo Bufo
0.50
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for AKT2 (RAC-beta serine/threonine-protein kinase). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: AKT2 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.