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Compounds That Target AKT3

AKT serine/threonine kinase 3 · 17 compounds in BiohacksAI corpus

AKT3 (AKT serine/threonine kinase 3) is a protein kinase involved in intracellular signal transduction. Kinases phosphorylate downstream substrates to regulate cell growth, survival, and metabolism. The 17 compounds targeting AKT3 include both pharmaceutical inhibitors and natural compounds with evidence of kinase modulation, ranked by evidence strength from the BiohacksAI corpus.

Most Studied Compounds for AKT3
11+
studies
All 17 Compounds — Ranked by Evidence
1
Midostaurin
3.85
confidence
2
Lestaurtinib
3.04
confidence
3
Pf 03758309
3.00
confidence
4
Ruboxistaurin
2.94
confidence
5
Mk 2206
2.83
confidence
6
Capivasertib
2.77
confidence
7
Gsk 690693
2.64
confidence
8
Gsk 1070916
2.20
confidence
9
Ipatasertib
2.20
confidence
10
A 443654
2.20
confidence
11
Enzastaurin
2.08
confidence
12
Gsk 269962a
2.08
confidence
13
Uprosertib
1.95
confidence
14
Borussertib
1.95
confidence
15
Afuresertib
1.79
confidence
16
Gw770249x
1.79
confidence
11+
studies
1.10
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for AKT3 (AKT serine/threonine kinase 3). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: AKT3 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.