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BiohacksAI/Targets/ARAF/Compounds

Compounds That Target ARAF

A-Raf proto-oncogene, serine/threonine kinase · 8 compounds in BiohacksAI corpus

ARAF (A-Raf proto-oncogene, serine/threonine kinase) is a receptor that mediates ligand-dependent signaling relevant to physiology, behavior, and metabolism. The 8 compounds with documented ARAF interactions span synthetic agonists, antagonists, and natural ligands identified through BindingDB binding assays and PubMed literature in the BiohacksAI corpus.

View ARAF target page →UniProt: P10398 ↗
Most Studied Compounds for ARAF
1
Sorafenib
300+
studies
2
Vemurafenib
298+
studies
All 8 Compounds — Ranked by Evidence
1
Dabrafenib
3.30
confidence
2
Gw305074x
3.14
confidence
3
Rebastinib
2.20
confidence
4
Ly 3009120
2.08
confidence
5
Bafetinib
1.95
confidence
6
Naporafenib
1.95
confidence
7
Vemurafenib
298+
studies
1.61
confidence
8
Sorafenib
300+
studies
1.39
confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for ARAF (A-Raf proto-oncogene, serine/threonine kinase). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: ARAF target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.