Compounds That Target CAMKK2

calcium/calmodulin dependent protein kinase kinase 2 · 124 compounds in BiohacksAI corpus

CAMKK2 (calcium/calmodulin dependent protein kinase kinase 2) is a protein kinase involved in intracellular signal transduction. Kinases phosphorylate downstream substrates to regulate cell growth, survival, and metabolism. The 124 compounds targeting CAMKK2 include both pharmaceutical inhibitors and natural compounds with evidence of kinase modulation, ranked by evidence strength from the BiohacksAI corpus.

View CAMKK2 target page →UniProt: Q96RR4 ↗

Most Studied Compounds for CAMKK2

Allium Sativum

500+

studies

Axitinib

298+

studies

Crizotinib

298+

studies

Sp600125

117+

studies

All 52 Compounds — Ranked by Evidence

Alvocidib

4.52

confidence

Foretinib

4.34

confidence

Ponatinib

4.26

confidence

Ceritinib

4.19

confidence

Bosutinib

4.08

confidence

Bi 2536

4.01

confidence

Midostaurin

3.85

confidence

Brigatinib

3.81

confidence

Abemaciclib

3.66

confidence

Nintedanib

3.61

confidence

Pelitinib

3.50

confidence

Tae 684

3.43

confidence

Gilteritinib

3.40

confidence

Fedratinib

3.40

confidence

At 7519

3.33

confidence

Sp 600125

3.22

confidence

Alectinib

3.18

confidence

Jnj 7706621

3.09

confidence

Pacritinib

3.04

confidence

Filgotinib

3.04

confidence

Lestaurtinib

3.04

confidence

Pf 03758309

3.00

confidence

Volasertib

2.94

confidence

Ruboxistaurin

2.94

confidence

Danusertib

2.94

confidence

K 252a

2.83

confidence

Milciclib

2.77

confidence

Pha 665752

2.71

confidence

Crenolanib

2.71

confidence

Kw 2449

2.64

confidence

Ast 487

2.56

confidence

Lavendustin C

2.48

confidence

Gsk 650394

2.20

confidence

Su 014813

2.20

confidence

Enzastaurin

2.08

confidence

Asp 3026

2.08

confidence

Cyc 116

2.08

confidence

Rg 547

2.08

confidence

Pf 03814735

1.79

confidence

Ucn 01

1.79

confidence

Sp600125

117+

studies

1.10

confidence

Glycyrrhiza Uralensis

1.00

confidence

Glycine Max

1.00

confidence

Lycopus Lucidus

1.00

confidence

Agastache Rugosa

1.00

confidence

Allium Sativum

500+

studies

1.00

confidence

Aloe Vera

1.00

confidence

Bupleurum Chinense

1.00

confidence

Chaenomeles Speciosa

1.00

confidence

Gastrodia Elata

1.00

confidence

Axitinib

298+

studies

0.69

confidence

Crizotinib

298+

studies

0.69

confidence

The compounds above were identified through computational analysis of BindingDB binding assay data and PubMed literature for CAMKK2 (calcium/calmodulin dependent protein kinase kinase 2). Confidence scores reflect the strength and breadth of experimental evidence.

Explore related resources: CAMKK2 target overview · All biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.